DDInteract Logo Drug-Drug Interaction Application

This is a demonstration page for the Drug-Drug Interaction (DDInteract) application. For use with real patients, this application should be called from within an EHR system. For more information, contact your system administrator.

Information on this application is available at: https://ddi-cds.org/apps/

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Demo Simple Selection

This launches the application with just an anticoagulant. For more complex pre-defined scenarios, see the Demo Patients below.

Demo Patients

The patients below are test patients that are not real patient data and can be used for demonstration, testing, or training purposes.


Patient Patient Id DOB Notes
Allen, Carol G smart-1577780 26 Dec 1963
  • WARFARIN
  • Mixed Drug with Aspirin (XX mg)
  • CLOPIDOGREL
  • esomeprazole 2.5 MG
  • 08/30/2023 - ibuprofen 400 MG / oxycodone hydrochloride 5 MG Oral Tablet
  • 24 HR naproxen 375 MG Extended Release Oral Tablet
  • 24 HR venlafaxine 75 MG Extended Release Capsule [Effexor]
  • venlafaxine 75 MG Oral Tablet
 Launch!
Black, Ruth C smart-665677 23 Aug 1951
  • apixaban 2.5 MG
  • aspirin 325 MG / oxyCODONE hydrochloride 2.25 MG / oxyCODONE terephthalate 0.19 MG Oral Tablet
Launch!
Scenario, A 14803 14 Feb 1948
  • warfarin sodium 5 MG Oral Tablet
 Launch!
Scenario, B 14806 03 Feb 1953
  • warfarin sodium 5 MG Oral Tablet
  • Gastrointestinal Hemorrhage
 Launch!
Scenario, C 15056 27 Feb 1952
  • Pradaxa 20 MG Oral Pellet
 Launch!
Scenario, D 15057 27 Feb 1961
  • On Pradaxa 20 MG Oral Pellet
 Launch!
Scenario, E 15058 27 Feb 1972
  • On rivaroxaban 1 MG/ML [Xarelto]
 Launch!
Scenario, F 15059 27 Feb 1941
  • On edoxaban 15 MG [Savaysa]
 Launch!

Risk Factors

Risk Factor Log Value
AGE 0.916
ANTI_PLATELET 0.669
ASPIRIN 0.27
CORTICOSTEROID 0.521
ON_PPI -0.4
PREVIOUS_BLEEDING 1.636

Medication Values

Description Strength Cost Rx Cui Treatment Type Risk Ratio Log Value
bupropion (Wellbutrin) 100 mg $ 42347 antidepressant 1.0 0.0
citalopram (Celexa) 20 mg $ 2556 antidepressant 1.364 0.31
desvenlafaxine (Pristiq) 50 mg $$ 734064 antidepressant 1.502 0.407
duloxetine (Cymbalta) 60 mg $ 72625 antidepressant 1.316 0.275
escitalopram (Lexapro) 10 mg $ 321988 antidepressant 1.352 0.302
fluoxetine (Prozac) 20 mg $ 4493 antidepressant 1.331 0.286
fluvoxamine (Luvox) 100 mg $ 42355 antidepressant 1.326 0.282
mirtazapine (Remeron) 15 mg $ 15996 antidepressant 1.144 0.135
paroxetine (Paxel) 20 mg $ 32937 antidepressant 1.291 0.255
sertraline (Zoloft) 50 mg $ 36437 antidepressant 1.29 0.255
venlafaxine (Effexor) 75 mg $$ 39786 antidepressant 1.502 0.407
apixaban 1364430 oralAnticoagulant 1.155 0.144
dabigatran 1546356 oralAnticoagulant 2.995 1.097
dabigatran etexilate 1037042 oralAnticoagulant 2.995 1.097
edoxaban 1599538 oralAnticoagulant 3.309 1.197
rivaroxaban 1114195 oralAnticoagulant 3.15 1.147
warfarin 11289 oralAnticoagulant 1.995 0.691
celecoxib (Celebrex) 200 mg $$ 140587 oralNsaid 1.161 0.149
diclofenac (Voltaren) oral 35 mg $ 3355 oralNsaid 3.418 1.229
diflunisal (Dolobid) 500 mg $ 3393 oralNsaid 1.31 0.27
etodolac (Lodine) 200 mg $$ 24605 oralNsaid 5.516 1.708
fenoprofen (Nalfon) 200 mg $$$ 4331 oralNsaid 4.31 1.461
ibuprofen (Motrin) 400 mg $ 5640 oralNsaid 2.276 0.822
indomethacin (Indocin) 75 mg $ 5781 oralNsaid 5.516 1.708
ketoprofen (Orudis) 25 mg $$ 6142 oralNsaid 4.841 1.577
ketorolac (Toradol) 10 mg $$ 35827 oralNsaid 20.669 3.029
mefenamic acid (Ponstel) 250 mg $ 257844 oralNsaid 1.31 0.27
meloxicam (Mobic) 7.5 mg $$ 41493 oralNsaid 6.851 1.924
nabumetone (Relafen) 500 mg $ 31448 oralNsaid 1.31 0.27
naproxen (Aleve / Naprosyn) 200 mg $ 7258 oralNsaid 4.31 1.461
oxaprozin (Daypro) 300 mg $ 32613 oralNsaid 4.31 1.461
piroxicam (Feldene) 20 mg $$ 8356 oralNsaid 9.236 2.223
sulindac (Clinoril) 150 mg $$ 10237 oralNsaid 5.516 1.708
tolmetin (Tolectin) 400 mg $$ 10636 oralNsaid 5.516 1.708
acetaminophen (Tylenol) $ 570070 other
diclofenac (Voltaren) 2% gel $$ 855635 other
lidocaine (Lidoderm) 5% patch $$$ 1011705 other
oxycodone (Roxicodone) $ 1049623 other
dexlansoprazole 30 mg $$ 816346 ppi 0.67 -0.4
esomeprazole 20 mg $ 283742 ppi 0.67 -0.4
esomeprazole strontium 49.3 mg $$$ 1435522 ppi 0.67 -0.4
lansoprazole 30 mg $ 17128 ppi 0.67 -0.4
omeprazole 20 mg $ 7646 ppi 0.67 -0.4
omeprazole / sodium bicarbonate 20 mg $$ 617777 ppi 0.67 -0.4
pantoprazole sodium 40 mg $$ 40790 ppi 0.67 -0.4
rabeprazole 20 mg $$ 114979 ppi 0.67 -0.4
rabeprazole sodium 20 mg $$ 226868 ppi 0.67 -0.4

Value Sets

Group Value Set
Aspirin 2.16.840.1.113762.1.4.1213.107
Anticoagulant 2.16.840.1.113762.1.4.1213.109
Antiplatelet 2.16.840.1.113762.1.4.1213.113
Corticosteroids 2.16.840.1.113762.1.4.1213.110
GI Bleed 2.16.840.1.113762.1.4.1213.123
NSAID 2.16.840.1.113762.1.4.1213.114
PPI 2.16.840.1.113762.1.4.1213.112
SSRI 2.16.840.1.113762.1.4.1213.111
v. 2025.11.03.0